Clinical Genomic, phenotype and epigenetic insights into the pathology, autoimmunity and weight management of patients with Myasthenia Gravis (Review)

Myasthenia Gravis (MG) is an autoimmune disease that affects neuromuscular junctions and characterized by muscle weakness as a result of autoantibodies against certain proteins. As heterogeneous disorder, MG presents with different types, including neonatal, ocular generalized in both juveniles adults. Different types antibodies serve role how presents. The main biological characteristic the production muscular acetylcholine receptor; however, other antibody have been associated disorder. thymus gland has established thymectomy possible treatment disease, along traditional medication such pyridostigmine bromide (Mestinon) immunosuppresants. In recent years, steps made towards developing more sensitive diagnostic methods. Additionally, novel treatments demonstrated promising results. Developing new assays may lead to increased understanding unravelling genetic pathway leads development diseases.